]★遺傳性乳癌小百科
1. 佔全部乳癌個案5至10%2. 與BRCA1或BRCA2任何基因出現突變有關,可遺傳自父或母
3. 帶有BRCA1突變基因的人,約六成半會於70歲前乳癌發病,近四成會患卵巢癌;帶有BRCA2突變基因的人,約四成半會於70歲前乳癌發病,男性患乳癌機會是6%(一般男性隻是1%)
4. 以往會考慮全乳房切除「預防」乳癌病發,可減少九成患癌機會,但留在皮下組織的乳腺仍有機會變成癌細胞,現時開始嘗試以磁力共振定期檢查,以期及早找出癌細胞。另外,參考特定乳癌病人服用Tamoxifen後復發率減低的研究,藥物或許是預防帶有突變基因者乳癌病發的方法,但尚待研究證實
5. BRCA1突變基因同時增加男士患前列腺癌及大腸癌機會;BRCA2突變基因會增加患上胰癌及前列腺癌機會 好貼必看,精華貼必回,感恩。
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